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The team of carbazoles confirmed nanomolar affinities with the CB1 receptor and behaved as entire agonists in cAMP accumulation assays. They circumvent the structural capabilities described in the NpSG by scaffold hopping. This new course of synthetic cannabinoids needs to be more researched to completely investigate its SARs and potential for abus… Read More

The team of carbazoles confirmed nanomolar affinities for the CB1 receptor and behaved as full agonists in cAMP accumulation assays. They circumvent the structural options explained during the NpSG by scaffold hopping. This new class of synthetic cannabinoids needs to be further examined to fully examine its SARs and prospective for abuse. The curr… Read More